• Another heroic set of studies

  2024-04-10

  

  Another heroic set of studies combining retrodialysis with electrophysiological recording at two distinct brain sites further indicated that the estradiol-induced increase in auditory-evoked firing in NCM also enhanced the selectivity of auditory-evoked responses in the downstream sensorimotor nucle

• The approach of enzymatically converting an analyte

  2024-04-10

  

  The approach of enzymatically converting an analyte and detecting it by the resulting small pH changes near the reduced graphene oxide (rGO) surface has successfully been pursued in case of urea (Piccinini et al., 2017). Furthermore, this work reported that electrostatic layer-by-layer (LbL) assembl

• br Material and methods br

  2024-04-10

  

  Material and methods Results Discussion Asparagine, arginine, leucine, methionine, and glutamine are the essential (R)-baclofen for cancer cells and intensively investigated for the development of selective targeted therapeutics. Among them, asparagine depleting bacterial enzyme asparagina

• br STAR Methods br AMPK A Therapeutic Target in the

  2024-04-10

  

  STAR★Methods AMPK: A Therapeutic Target in the β Cell? Loss of pancreatic β cell function is a hallmark of the transition to a diagnosis of T2DM (see Glossary) 1, 2, 3, 4. AMPK activation has gained attention for the treatment of hyperglycemia in prediabetes as an insulin-sensitizing agent bec

• br Conclusion P gingivalis expresses various exopeptidases i

  2024-04-09

  

  Conclusion P. gingivalis expresses various exopeptidases, i.e., DPP4, DPP5, DPP7, DPP11, PtpA, and AOP, in periplasmic space, which produce di- and tri-peptides from most oligopeptides. This oligopeptide processing step is important as an extracellular event in the TMC125 receptor of asaccharoly

• Introduction Cancer which is responsible for a million death

  2024-04-09

  

  Introduction Cancer, which is responsible for a million deaths each year, is universally feared, and approximately 50% of newly diagnosed cases can be cured [1]. The existing cancer treatments, including surgery, chemotherapy, radiotherapy or a combination of them, are quickly losing efficacy. The

• Several genes related to metabolism post transcriptional reg

  2024-04-09

  

  Several genes related to metabolism, post-transcriptional regulation, chromatin structure, and signaling pathways are required for the sexual development and virulence of G. zeae (Baldwin et al., 2010, Bluhm et al., 2007, Ding et al., 2009, Han et al., 2007, Hou et al., 2002, Jenczmionka et al., 200

• While high fat diet models of

  2024-04-09

  

  While high-fat diet models of insulin resistance are acceptable approaches for the study of pre-diabetes in humans, they are not suitable for modeling progression towards established type2 diabetes. The pattern of activation of the lipoxygenase pathway in pre-clinical models of type2 diabetes has no

• br Introducing toll like receptors TLRs are the

  2024-04-09

  

  Introducing toll like receptors TLRs are the most important receptors which are expressed on the cytoplasmic and internal vesicles membrane. They have a similar structure including a leucine-rich repeats (LRRs) domain which is out of MK-8776 membrane, a hydrophobic transmembrane and a toll/inter

• br Genetic analysis of polarity complexes

  2024-04-08

  

  Genetic analysis of polarity complexes Model organisms such as Caenorhabditis elegans and Drosophila melanogaster provide useful means of describing basic biological processes. They lend themselves particularly well to addressing some of the questions arising in this field because of their struct

• br Results A total of

  2024-04-08

  

  Results A total of 126 respondents completed the survey (68.5% response rate), with at least 65% response rate from each of the four represented sectors (denominators represent the total constituent body of the organization or the total attendees of the meeting): PUC 24 out of 37 (65%), SPUNZA 33

• br Natriuretic peptides and neprilysin Left ventricular

  2024-04-08

  

  Natriuretic peptides and neprilysin Left ventricular systolic function, most commonly due to myocardial damage as a consequence of coronary artery disease, hypertension or both, and leading to sustained, pathological activation of the renin angiotensin tolbutamide system (RAAS) and sympathetic n

• monocarboxylate transporters Clinical observations of indivi

  2024-04-08

  

  Clinical observations of individuals with a decrease in 12-LOX monocarboxylate transporters are consistent with 12-LOX potentiating platelet activation and thrombus formation [40]. However, the relative contribution of 12-LOX to these complex disorders cannot be fully elucidated in the absence of a

• Liao and van Linden et

  2024-04-08

  

  Liao [47] and van Linden et al. [48] divided the gap between the N-terminal and C-terminal lobes into a front cleft or pocket, a gate area, and a back cleft. The back pocket corresponds to the gate area and the back cleft. The front cleft includes the Gly-rich loop, the hinge, the linker connecting

• Gliomas and Aldehyde Dehydrogenase Aldehyde

  2024-04-08

  

  Gliomas and Aldehyde Dehydrogenase Aldehyde dehydrogenases (ALDHs) are key metabolic enzymes involved in regulation of glycolysis/gluconeogenesis pathways as well as in the detoxification of endogenous and exogenous aldehydes, regulating cell function and homeostasis. ALDHs play important roles in

15940 records 176/1063 page Previous Next First page 上5页 176177178179180 下5页 Last page